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Immune Signaling Pathways
Cancer Signaling Pathways
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Gene Symbol
e.g.
SHC1
Protein Name
e.g.
EGF receptor
Accession Number
e.g.
NP_002077.1
Pathway Name
Select a pathway
Alpha6 Beta4 Integrin
AR
B Cell Receptor
EGFR1
Hedgehog
ID
IL-1
IL-2
IL-3
IL-4
IL-5
IL-6
IL-7
IL-9
Kit Receptor
Notch
TGF beta Receptor
TNF alpha/NF-kB
T Cell Receptor
Wnt
Statistics
Curated Pathways
20
Molecules Involved
963
Physical Interactions
1649
Genes Transcriptionally Regulated
6137
Transport
148
Enzyme Catalysis
729
PubMed Citations
10209
'NetPath'
is a curated resource of signal transduction pathways in humans. It is a collaboration between the
PandeyLab
at Johns Hopkins University and the
Institute of Bioinformatics
. At this time, 10 immune and 10 cancer signaling pathways are available. The 10 cancer signaling pathways were developed in collaboration with the
Computational Biology Center
at
Memorial Sloan-Kettering Cancer Center
and with
Gary Bader's lab
at the University of Toronto for the
'
Cancer Cell Map
'
.
All 20 pathways are freely available in
BioPAX
,
PSI-MI
and
SBML
formats at this website.
BioPAX
is an emerging standard for pathway data exchange. The 10 cancer signaling pathways are also available for download and browsing from the Cancer Cell Map project website. The pathways are freely available under an adaptive Creative Commons License which stipulates that the pathways may be used if adequate credit is given to the authors. These pathways are unpublished at this time, please cite the websites until the pathways are described in a publication.
Feedback on the NetPath website and its contents can be sent to
info@netpath.org
.
This is a joint project between:
and