Criteria for NetSlim

NetSlim is developed using the following inclusion criteria to extract a high confidence set of reactions from NetPath pathways.

  Reactions supported by at least 2 research articles
  Reactions reported in atleast 2 cell types
  Protein-protein interactions reported through high-throughput analyses, as well as induced PTMs identified using mass
spectrometry are included if they are supported by findings from targeted biochemical studies
  Components of known protein complexes even if they do not meet 2 research article criteria
  Molecules or reactions described in expert review articles
A schematic representation of NetSlim criteria is depicted below.