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Criteria for NetSlim
NetSlim is developed using the following inclusion criteria to extract a high confidence set of reactions from NetPath pathways. |
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Reactions supported by at least 2 research articles |
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Reactions reported in atleast 2 cell types |
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Protein-protein interactions reported through high-throughput analyses, as well as induced PTMs identified using mass
spectrometry are included if they are supported by findings from targeted biochemical studies |
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Components of known protein complexes even if they do not meet 2 research article criteria |
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Molecules or reactions described in expert review articles |
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A schematic representation of NetSlim criteria is depicted below. |