| Interleukin-2 belongs to a family of cytokines, which includes IL-4, IL-7, IL-9, IL-15 and IL-21. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 receptor beta (CD122) and a common gamma chain (γc), which is shared by all members of this family of cytokines. Binding of IL-2 activates the Ras/MAPK, JAK/Stat and PI 3-kinase/Akt signaling modules. |
| Pathway Statistics |
| Molecules Involved | 68 |
| Physical Interactions | 68 |
| Enzyme Catalysis | 76 |
| Transport | 11 |
| Genes Transcriptionally Regulated | 848 |
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