| Interleukin-3 belongs to a family of cytokines, which includes IL-5 and GM-CSF. It signals through a receptor complex comprising of an IL-3 specific IL-3 receptor alpha subunit (IL3RA) and a common beta chain, which is shared between all members of this cytokine family. Binding of IL-3 to IL3RA recruits the beta chain to the complex, which activates the JAK/STAT, MAPK and PI 3-kinase signaling modules. |
| Pathway Statistics |
| Molecules Involved | 79 |
| Physical Interactions | 65 |
| Enzyme Catalysis | 52 |
| Transport | 5 |
| Genes Transcriptionally Regulated | 53 |
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