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Androgen Receptor Signaling Pathway  Accession number : NetPath_2
The androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among others, dimerize and bind to DNA. Its ligands include testosterone, dehydroepiandrosterone and androstenedione. Stimulation of the receptor activates the SMAD signaling module.
  Pathway Statistics
 Molecules Involved  97
 Physical Interactions  80
 Enzyme Catalysis  14
 Transport  3
 Genes Transcriptionally Regulated  603


  Molecules Involved in Androgen Receptor signaling pathway (Total = 97)
 AES  AKT1  APPL1  AR  ATF2  BAG1  BRCA1  CALR  CASP1  CASP3  CASP7  CASP8  CAV1  CCND1  CCNE1
 CCNH  CDC2  CDC25B  CDC37  CDK9  COX5B  CREBBP  CTNNB1  EP300  ESR1  ETV5  FHL2  FLNA  GAPDH  GTF2F1
 GTF2F2  GTF2H1  HDAC1  HIPK3  HSP90AA1  HSPA1A  HTATIP  IARS  IL6ST  JUN  MAPK1  MDM2  MNAT1  MYST2  NCOA1
 NCOA2  NCOA3  NCOA4  NCOR2  NR0B2  NR2C2  NR3C1  NR5A1  NRIP1  NSD1  PA2G4  PAK6  PCAF  PIAS1  PIAS2
 PIAS3  PIAS4  PNRC1  POU2F1  PRMT1  PSMC3IP  PTEN  PXN  RAC3  RAD54L2  RAN  RANBP9  RB1  RCHY1  RELA
 RNF14  RNF4  RUNX1  RUNX2  SENP1  SIN3A  SLC25A4  SMAD3  SMAD4  SP1  SPDEF  SRY  STAT3  STUB1  SVIL
 TGFB1I1  TGIF  TMF1  UBE2I  UBE3A  UXT  ZNF278


  Reactions in Androgen Receptor pathway (Total = 97)
   Physical Interactions
   Enzyme Catalysis
   Transport

  Genes Transcriptionally Regulated by Androgen Receptor pathway (Total = 603)
   Upregulated genes
   Downregulated genes

Download Pathway Download Transcriptionally Regulated Genes






Last updated: Feb 18, 2009
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