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IL-9 Signaling Pathway  Accession number : NetPath_20
Interleukin-9 belongs to a family of cytokines, which includes IL-2, IL-4, IL-7, IL-15 and IL-21. It signals through a receptor complex consisting of an IL-9 receptor (IL9R) and a common gamma chain that is shared between all members of this family. IL-9 activates Jak/STAT and MAPK signaling modules.
  Pathway Statistics
 Molecules Involved  23
 Physical Interactions  14
 Enzyme Catalysis  20
 Transport  4
 Genes Transcriptionally Regulated  26


  Molecules Involved in IL-9 signaling pathway (Total = 23)
 AKT1  GRB2  HTATIP  IL2RG  IL9  IL9R  IRS1  IRS2  JAK1  JAK3  MAP2K1  MAP2K2  MAPK1  MAPK3  PIK3R1
 PTPN11  SHC1  STAT1  STAT3  STAT5A  STAT5B  TYK2  VCP


  Reactions in IL-9 pathway (Total = 38)
   Physical Interactions
   Enzyme Catalysis
   Transport

  Genes Transcriptionally Regulated by IL-9 pathway (Total = 26)
   Upregulated genes
   Downregulated genes

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Last updated: Oct 23, 2009

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